Quizalofop-p-ethyl: Herbicides used to control soybean fields

Aug 25, 2023

Quizalofop-p-ethyl was initially created by Nissan Chemical Corporation and is currently known as quizalofop-P-isomer in the market. It serves as an effective solution for grass weed management in numerous prominent broadleaf crops, including soybean, various food and beverages, rapeseed, sunflower, sugar beet, and cotton.

Europe, South America, and Asia Pacific are the primary regions where quizalofop is widely utilized.

With the advent of glyphosate-resistant soybean seeds and the widespread use of glyphosate, several weed species have acquired increasing tolerance to this herbicide over the years. As a result, quizalofop-p-ethyl has emerged as an effective alternative solution in tackling these resilient weeds.

What is Quizalofop-p-ethyl

What is Quizalofop-p-ethyl?

Quizalofop-p-ethyl is a racemate with an asymmetric carbon atom at the alpha position of the propionic acid moiety. The active isomer is the R enantiomer, known as quizalofop-p-ethyl.

Quizalofop-p-ethyl acts by inhibiting the activity of acetyl-CoA carboxylase (ACCase), an enzyme necessary for the synthesis of fatty acids in plants. By disrupting this process, herbicides interfere with the growth and development of sensitive grass weeds, eventually causing their death.

HRAC Group 1 (Inhibition of Acetyl CoA Carboxylase)

Quizalofop-P-ethyl is a systemic herbicide known for its effective weed control properties. When applied to foliage, it quickly absorbs into the plant tissues, reaching the meristem tissue within 24 hours. By inhibiting ACCase in the meristem tissue, this herbicide effectively halts weed growth and ensures a healthy crop.

Quizalofop-P-ethyl stands out among other herbicides due to its remarkable selectivity. By targeting the ACCase in grass family plants, specifically the active form of quizalofop-P, it effectively inhibits their growth while leaving non-gramineous crops unaffected. This exceptional level of safety makes quizalofop-P-ethyl an ideal choice for herbicidal applications..

Promising herbicide in controlling volunteer corn in soybean field

Quizalofop-ethyl is highly safe to broadleaf crops such as soybean, sugar beet, cotton and sunflower. It is widely used in more than 40 countries around the world.

In the U.S., most sales go into soybeans to specifically control volunteer corn. Brazil is the largest agricultural market in the world. Quizalofop-p-ethyl is used to control weeds in cereals as a pre-sow burnout treatment or as a post-emergency application.

Volunteer corn, a remnant from the previous crop, poses a significant challenge in soybean fields. It aggressively competes with soybeans for essential resources such as water, nutrients, and sunlight. Furthermore, the presence of volunteer corn roots serves as a food source for corn rootworm larvae, exacerbating the risks associated with its growth.

Quizalofop-ethyl is also very popular in Asia. The product has been sold for many years, and local farmers are satisfied with the good results of the product. It is mainly used to control broad-leaved gramineous crops such as peanut, rape, cotton, watermelon, Chinese cabbage and sesame.


Available formulations:  Quizalofop-P-ethyl 50g/l EC; Quizalofop-P-ethyl 100g/l EC

The birth of the new compound Quizalofop

Today, Nissan remains an important supplier of quizalofop-ethyl, mainly through the Targa brand. Like any new chemical, its discovery and development took a long time. In 1975, Dr. Koichi Suzuki was a young scientist who had just joined Nissan Chemical.

At that time, Nissan Chemical’s agrochemical research was still in its infancy, and its reputation was not high. Mr. Koichi and his colleagues had a strong desire to develop a compound that would shine on the world stage.

After discovering the new compound, quizalofop-p-ethyl, they tested its efficacy on every weed species and in as many areas as possible.

They focused in particular on a weed called Johnson’s Grass, which at the time was a troublesome weed in the southern United States, and efficacy tests had shown encouraging results. Since then, TARGA has been sold all over the world and cooperates with multinational companies to further expand the market.

Dr. Koichi Suzuki expressed his pride in the development of TARGA, acknowledging that it has not only contributed to their growth as researchers but has also played a significant role in the advancement of Nissan Chemical as a company.

Koichi Suzuki expressed

Glyphosate-resistant (GR) weeds control in soybean field

The introduction of GR genetically modified crops has had a transformative impact on weed management practices. These crops provide farmers with effective and cost-effective weed control tools.

As a result, the adoption of GM crops by the US and Brazilian agricultural sectors has significantly increased the use of glyphosate while reducing reliance on other herbicides. This shift in approach has revolutionized weed management strategies and has brought numerous benefits to farmers.

The widespread use of glyphosate has led to the emergence of resistant weed species, especially in soybean fields in Brazil. To solve this problem, an alternative solution in the form of quizalofop-p-ethyl is available and can be applied accordingly.

Species Popular name
Lolim perenne ssp.multiflorum Ryegrass
Conyza bonariensis Hairy fleabane
Conyza canadensis Horseweed
Digitaria insularis Sourgrass
Eleusine indica Goosegrass
Amaranthus hybridus Smooth pigweed
This table lists (incompletely) some of the Glyphosate-resistant weed species in soybean field, Brazil.


Recent developments in herbicide tolerance technology are expected to benefit quizalofop-P-ethyl sales in the coming years. Presumably, as more multinational companies start to launch GM seeds on a large scale, accompanied by potential glyphosate resistance problems, the demand for quizalofop-P-ethyl will remain high.