Difenoconazole: An Effective Treatment For Fungal Infections

Mar 03, 2023

Difenoconazole is a broad-spectrum fungicide that controls a wide variety of fungi – including members of the Ascomycetes, Basidiomycetes, and Deuteromycetes families. It acts as a seed treatment, foliar spray, and systemic fungicide.

It is taken up through the surface of the infected plant and is translocated to all parts of the plant. It has a curative effect and a preventative effect.

Difenoconazole can be applied to winter wheat, oilseed rape, Brussels sprouts, cabbage, broccoli/calabrese, and cauliflower. It controls various fungi including Septoria tritici, Brown Rust, Light Leaf Spot, Leaf Spot, Pod Spot, Ring Spot, and Stem canker. It also prevents Ear Discolouration in winter wheat.

In this article, we will provide an overview of difenoconazole, including its history, mode of action, and uses.

Introduction of Properties of Difenoconazole

Difenoconazole is a systemic fungicide that belongs to triazole fungicide. It is an inhibitor of sterol demethylation. The mode of action is to inhibit the biosynthesis of ergosterol by interfering with the C14 demethylation of pathogenic bacteria cells so that the sterol stays in the cell membrane, damaging the physiological function of the membrane and causing the death of fungi.

Difenoconazole has a wide germicidal spectrum, internal absorption conductivity, long efficacy, multiple dosage forms, and high safety. It can be mixed with many other fungicides, such as Propiconazole, Azoxystrobin, etc. The common types of pesticide formulation are Difenoconazole 25%EC, Difenoconazole 15% + Propiconazole 15%SC, and Difenoconazole 10%WG.

History of Difenoconazole

Difenoconazole is a broad-spectrum fungicide that is used to control a wide variety of diseases in plants. It is most commonly used to control powdery mildew, but it can also be used to control black spots, rust, and other fungal diseases. Difenoconazole was first synthesized in 1989 by Ciba-Geigy and has been used extensively in agriculture and horticulture since then.

In 1999, Syngenta Company registered 10% Difenoconazole WG for the first time. By 2005, the sales volume of Difenoconazole was 135 million dollars, and in 2007, the sales volume was 195 million dollars. Global sales in 2016 were $330 million. The market has shown a steady growth trend over the years.

Difenoconazole is effective because it prevents fungi from growing and spreading. It does this by inhibiting the production of sterols, which are essential for the cell membranes of fungi. This prevents the fungi from growing and spreading and eventually leads to their death.

Difenoconazole chemical structure

How does difenoconazole work?

Difenoconazole is taken up by the plant and acts on the fungal pathogen during penetration and haustoria formation. It stops the development of fungi by interfering with the biosynthesis of sterols in cell membranes.

Although the mode of action permits protective and curative use, it is recommended to apply the product early enough to avoid irreversible crop damage and build-up of the disease.  

Uses for Difenoconazole

Difenoconazole is mainly used for foliar treatment and seed treatment. The dosage of Difenoconazole 10%WG was 30 ~ 125g/hm2, which was mainly used for stem and leaf treatment.

The application of Difenoconazole is mainly used to control pear black star disease, apple spot defoliation disease, tomato early blight, watermelon cranberry blight, pepper anthracnose, strawberry powdery mildew, grape anthracnose, blackpox disease, citrus scab disease, etc.

1. Pear black star disease:

At the early stage of onset, 14.3 ~ 16.6g (effective concentration 14.3 ~ 16.6mg/L) is added to 100L water. When the disease is severe, the concentration can be increased. It is recommended to add 20 ~ 33g of preparation per 100L of water (effective concentration 20 ~ 33mg/L) and spray continuously for 2 ~ 3 times at an interval of 7 ~ 14 days.

Pear black star disease

2. Apple spot deciduous disease:

At the beginning of the disease, 33 ~ 40g of Difenoconazole formulation (effective concentration of 33 ~ 40mg/L) is added to 100L water. At the severe disease, 1,500 ~ 2000 times the liquid or 50 ~ 66.7g of Difenoconazole formulation (effective concentration of 50 ~ 66.7mg/L) is added to 100L water, and sprayed continuously for 2 ~ 3 times at an interval of 7 ~ 14 days.

Apple spot deciduous disease

3. Grape anthracnose, blackpox disease:

Difenoconazole is an effective fungicide for the control of grape anthracnose, blackpox disease. Use every 100L water with formulation 50 ~ 66.7g (effective concentration 50 ~ 66.7mg/L).

4. Citrus scab:

Difenoconazole is an effective fungicide for the control of citrus scab. Use every 100L water with formulation 40-50g (effective concentration 40-50 mg/L) spray.

5. Watermelon vine blight:

Difenoconazole is an effective fungicide for the control of watermelon vine blight. Use formulation 50 ~ 80g per mu (active ingredient 5 ~ 8g).

6. Strawberry powdery mildew:

Difenoconazole is an effective fungicide for the control of strawberry powdery mildew. Use formulation 20 ~ 40g per mu (effective ingredient 2 ~ 4g).

7. Tomato early disease:

Difenoconazole is an effective fungicide for the control of tomato early disease. At the beginning of the disease, use every 100L of water with formulation 83 ~ 125g (effective concentration 83 ~ 125mg/L), or use formulation 4.0 ~ 60g per mu (effective ingredient 4 ~ 6g).

8. Pepper anthracnose:

Difenoconazole is an effective fungicide for the control of Pepper anthracnose. Use every 100L water with formulation 83 ~ 125g (effective concentration 83 ~ 125mg/L), or per mu use formulation 40 ~ 60g (effective ingredient 4 ~ 6g).

To Sum Up

Difenoconazole is a safe and environmentally friendly option for those looking for a fungicide. Heben is a world-leading manufacturer of agrochemical active ingredients and formulated products. Our products are used in over 140 countries and have been trusted by millions of companies worldwide.

If you’re looking for the best Difenoconazole products or any other agrochemical needs, Heben is the perfect solution. Give us a call at 86 (0)577 55882935 or email us at info@hb-p.com to request free samples today!